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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TTK
All Species:
13.03
Human Site:
T468
Identified Species:
23.89
UniProt:
P33981
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P33981
NP_003309.2
857
97072
T468
D
Y
M
S
C
F
R
T
P
V
V
K
N
D
F
Chimpanzee
Pan troglodytes
XP_001146752
857
97034
T468
D
Y
M
S
C
F
R
T
P
V
V
K
N
D
F
Rhesus Macaque
Macaca mulatta
XP_001111082
778
87619
V429
H
T
T
F
E
Q
P
V
F
S
V
S
K
Q
S
Dog
Lupus familis
XP_539016
855
96614
T466
D
Y
M
N
C
F
R
T
P
V
V
K
N
D
F
Cat
Felis silvestris
Mouse
Mus musculus
P35761
856
96192
C464
S
L
D
D
Y
M
K
C
F
K
T
P
V
V
K
Rat
Rattus norvegicus
NP_001101642
835
94323
T446
D
Y
M
K
C
F
K
T
S
V
V
K
N
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512474
935
104827
R471
T
C
G
T
P
S
S
R
T
V
D
D
Y
M
A
Chicken
Gallus gallus
XP_419867
879
99691
P472
L
L
Y
V
C
G
T
P
S
S
T
C
T
D
Y
Frog
Xenopus laevis
NP_001082090
882
99060
P470
P
S
L
S
K
C
D
P
V
F
V
C
G
T
P
Zebra Danio
Brachydanio rerio
Q8AYG3
982
109993
E530
H
Q
K
P
F
S
K
E
T
S
S
E
W
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002301009
818
91361
Q443
K
V
N
G
K
L
Y
Q
R
L
G
K
I
G
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565160
777
86358
K428
D
C
T
I
Y
A
L
K
K
I
K
L
K
G
R
Baker's Yeast
Sacchar. cerevisiae
P54199
764
86809
V415
K
P
P
V
T
K
K
V
E
I
V
E
P
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
85.7
87.4
N.A.
74.3
76.9
N.A.
64.2
61
52.8
41.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
87.7
92.6
N.A.
84.8
85.6
N.A.
73.6
74.5
68.4
57
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
93.3
N.A.
0
73.3
N.A.
6.6
13.3
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
6.6
86.6
N.A.
13.3
20
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
23.1
N.A.
N.A.
22.9
22.7
N.A.
Protein Similarity:
40.2
N.A.
N.A.
42.3
44.5
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
16
0
0
39
8
0
8
0
0
0
16
0
0
0
% C
% Asp:
39
0
8
8
0
0
8
0
0
0
8
8
0
31
0
% D
% Glu:
0
0
0
0
8
0
0
8
8
0
0
16
0
8
0
% E
% Phe:
0
0
0
8
8
31
0
0
16
8
0
0
0
0
31
% F
% Gly:
0
0
8
8
0
8
0
0
0
0
8
0
8
16
0
% G
% His:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
16
0
0
8
0
8
% I
% Lys:
16
0
8
8
16
8
31
8
8
8
8
39
16
8
16
% K
% Leu:
8
16
8
0
0
8
8
0
0
8
0
8
0
0
0
% L
% Met:
0
0
31
0
0
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
8
8
0
0
0
0
0
0
0
0
31
0
0
% N
% Pro:
8
8
8
8
8
0
8
16
24
0
0
8
8
0
8
% P
% Gln:
0
8
0
0
0
8
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
24
8
8
0
0
0
0
0
8
% R
% Ser:
8
8
0
24
0
16
8
0
16
24
8
8
0
0
16
% S
% Thr:
8
8
16
8
8
0
8
31
16
0
16
0
8
8
0
% T
% Val:
0
8
0
16
0
0
0
16
8
39
54
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
31
8
0
16
0
8
0
0
0
0
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _